The Role of Alcoholics' Insight in Abstinence from Alcohol in Male Korean Alcohol Dependents

نویسندگان

  • Jong Sung Kim
  • Byoung Kang Park
  • Gap Jung Kim
  • Sung Soo Kim
  • Jin Gyu Jung
  • Mi Kyeong Oh
  • Jang Kyun Oh
چکیده

This study was performed to examine the relationship between the abstinence results of alcohol dependents after discharge and the level of insight at the time of discharge. 117 male Korean alcohol dependents discharged from a community-based alcohol treatment center were followed up to determine the initial months of abstinence on a successive basis (IMA), total months of abstinence during 12-month period (TMA), and complete abstinence for one full year after discharge. Analyses of abstinence results with adjustment for the differences in baseline characteristics were performed for subjects' insight levels (poor, fair and good). The mean IMA of patients with good insight was significantly (p<0.01) longer than that of patients with poor insight and TMA of patients with good insight was significantly (p<0.001) longer than that of others. Using patients with good insight as the reference, patients with poor insight showed an adjusted odds ratio (OR) of 0.07 (95% confidence interval [CI]=0.01-0.75, p<0.05) for complete abstinence for one full year after discharge and patients with fair insight, adjusted OR of 0.17 (95% CI=0.03-0.81, p<0.05). These results suggest that alcohol dependents' insight could be regarded as a factor related with abstinence.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Immunohistochemical localization of alcohol dehydrogenase (ADH) in the stomach before and after abstinence of alcohol in alcoholics--using confocal laser scanning microscopy.

Previous studies have reported some significant participation by gastric alcohol dehydrogenase (ADH) in alcohol metabolism, similar to that by hepatic ADH. However, the localization of this ADH in the stomach is not yet determined and there has been no study on the localization of ADH in the stomach of alcoholics before and after abstinence from alcohol. The aim of the present study was to reve...

متن کامل

Kinetics and isoforms of serum glutamate dehydrogenase in alcoholics.

AIMS The goal of this paper was to determine Glutamate dehydrogenase's (GLDH) increased activity and rapid decrease in alcoholics according to last consumption of alcohol as well as to confirm that quick normalisation cannot be a sign of hepatocyte necrosis and that GLDH from rough endoplasmic reticulum exists in the serum of alcoholics. METHODS GLDH activity was assessed in 238 alcoholics ad...

متن کامل

Psychological Effects of Alcohol Abuse

In fact alcohol is a toxic substance that has a direct effect on brain. Some of the most common mental disorders due to alcohol abuse are: Memory disorder: Hazardous amounts of alcohol may cause intoxication, impairment of memory so that the person who took a drunken accident may not remember the event. Periods of memory impairment in those with a history of alcohol addiction would also happen ...

متن کامل

Persistence of defective serotonergic and GABAergic controls of growth hormone secretion in long-term abstinent alcoholics.

In order to establish whether long-term abstinence from alcohol reverses the defective serotonergic and GABAergic controls of growth hormone (GH) secretion affecting alcoholic patients, the 5-HT1D serotonergic receptor agonist sumatriptan and the GABAergic agent gamma-hydroxybutyric acid (GHB) were administered to 12 normal men (32-49 years) and 22 non-depressed male alcoholic subjects (38-52 y...

متن کامل

Alcohol and Cognition; From Neurotoxicity Prevention to Cognitive Rehabilitation

Alcohol provokes different molecular pathways contributing to a clinically significant neurotoxicity in different brain areas. Affected cognition in alcoholics can influence both daily life functioning and alcohol craving management abilities. Preventing alcohol-induced neurotoxicity with different neuroprotective pharmacological interventions is receiving strong scientific backgrounds from pub...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 22  شماره 

صفحات  -

تاریخ انتشار 2007